VivoSep SEC is a newly developed line of SEC (Size Exclusion Chromatography) separation columns specifically designed for the separation of oligo/polyphenols with attached sugars and separation of large proteins. This is now possible in SEC on a purely steric basis without interference from adsorption effects. At the same time, the application range has been extended to a size range of around 100 to 1 million Daltons. Whereas previously a separation of up to 200kDa using just one buffer solution often required more than an hour, this can now be achieved within down to 15 minutes with a size range of up to 4.5 MDa. In addition, there is the wide usable temperature range from 10 to 90 oC
VivoSep SEC Columns therefore offer three major advantages, that you will not find on any other system that you can buy.:
- Higher separation performance in less time: By using pressure-stable filling materials, the columns are filled with smaller resin particles, resulting in separation rates of over 20,000 plates/m. This results in up to 4 times higher sample throughput.
- Larger Dalton rangeThe newly developed filling material now allows the separation of proteins over a range of 4 decades (!) from about 100 to greater than 1.00E+06 Da, depending on the column type.
- Lower costs and better environmental protection: The separation in VivoSep SEC is carried out in cost-effective, water-based running agents - the same for all size classes and with lower consumption due to the improved separation performance. This not only applies to samples of water-soluble proteins, but also when hydrophobic substructures are present
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